The construction industry is a principal consumer of raw materials and one of the biggest producers of greenhouse gases and waste. The reuse of carrier system elements in new building projects remains an underutilized strategy for reducing the construction sector’s environmental footprint. This research project develops algorithms to identify structural system geometries that make optimum use of existing component inventories. Full-scale prototypes are developed to demonstrate feasibility at the level of design detail. Finally, the environmental benefits of reuse are assessed using a life-cycle analysis.